Local Opportunities:

PhillyDH - A regional interest group for those interested in DH in Philadelphia and the Delaware Valley area. The Google Group contains announcements for events, projects, and jobs of interest in the area.
Website: http://phillydh.org/
Google Group: https://groups.google.com/forum/#!forum/phillydigitalhumanities

Digital Scholarship Center at Temple University - The Digital Scholarship Center is a space for collaborative work in areas of research and technology, digital humanities, digital arts, gaming, making, big data, and others. Their events are often open to the public.
Website: http://sites.temple.edu/tudsc/

GLAM Cafe - Work / Chat / Share / Relax. Are you interested in using digital media in the GLAM (Galleries, Libraries, Archives and Museums) field? Join other digital humanities enthusiasts the second Tuesday of each month for the GLAM Cafe, a coffee house style meetup with a rotating Center City location.
Website: http://www.meetup.com/GLAM-Cafe-Philadelphia/

Interactive Mechanics - A local company of web designers & developers with “the mission to work on meaningful digital projects for arts & culture, educational institutions, nonprofits, and care organizations.” In addition to offering services for building websites, digital exhibits, and mobile apps, they have also begun offering occasional workshops.
Website: http://interactivemechanics.com/
Workshops: http://interactivemechanics.ticketleap.com/ 

Keystone DHKeystoneDH is committed to advancing collaborative scholarship in the Digital Humanities among institutions of Higher Education. They host an annual conference in Pennsylvania during the summer.
Website: http://keystonedh.network/

Price Lab for Digital Humanities at UPenn - Established in 2015, the Price Lab for Digital Humanities supports innovative uses of technology in the study of history, art, and culture. Some of their events are open to the public.
Website: http://pricelab.sas.upenn.edu/

THATCamp Philly - An annual DH unconference since 2011, held in the fall.
Website: http://thatcampphilly.org/

National/International Opportunities:

Alliance of Digital Humanities Organizations (ADHO) Annual Conference - An annual DH conference since 1989. It is an international conference, so some years the location is closer than others. There is also an events calendar with information about other conferences and events of interest to the DH community.
Conference Website: http://adho.org/conference
Events Calendar: http://adho.org/events-calendar

centerNetcenterNet is an international network of digital humanities centers formed for cooperative and collaborative action to benefit digital humanities and allied fields in general, and centers as humanities cyberinfrastructure in particular.
Webiste: http://dhcenternet.org/

DHCommonsDHCommons, an initiative of centerNet, is an online hub focused on matching digital humanities projects seeking assistance with scholars interested in project collaboration.
Website: http://dhcommons.org/

Digital Humanities Summer Institute (University of Victoria) - The Digital Humanities Summer Institute provides an ideal environment for discussing and learning about new computing technologies and how they are influencing teaching, research, dissemination, creation, and preservation in different disciplines, via a community-based approach. A time of intensive coursework, seminars, and lectures, participants at DHSI share ideas and methods, and develop expertise in using advanced technologies.
Website: http://www.dhsi.org/